My interests are multidisciplinary in that they encompass
both research and regulatory affairs. My research interests
include the bio effects of ionizing and non-ionizing (including
ultrasound) radiation energy as a function of their physical
At the same time I have maintained an interest
in those areas of regulatory oversight of selected industries
under the purview of the U.S. Food and Drug Administration
(USFDA). Of particular consultative interests to me are
the USFDA regulations which govern the current good manufacturing
practices (i.e. CGMPs) of the industries involved in medical
devices, biotechnology, institutional review boards (IRBs)
and lasers. In addition to the foregoing over the last
several years I have led joint efforts to formulate biotechnology
research projects including UCLA, the USFDA, and the private
sector. These efforts gave dealt with research projects
in breast cancer diagnosis and treatment (currently at
the West LA VA Medical Center), the application of Fourier
Transform Infra-red (FTIR) spectroscopy to characterization
of mammalian cells, chromosomes, neoplastic tissue, and
selected polymers. The ultimate conclusion to these efforts
is the formation of a Cooperative Research and Development
Agreement (CRADA) under the auspices of the Federal Technology
Transfer Act of 1987.
- Roseboro, J.A.: “A Study of Alternatives to
Chemical Fumigation in Mediterranean Fruit-Fly (Drosophila
Melanogaster as Model) Disinfection,” JPL Publication
(81-Series), August 1981.
- Gammel, P.M.: Heyser, R.C.; Le Crosissette, D.H.;
Roseboro, J.A.; and Wilkson, R.L.: “The Temperature
and Frequency Dependence of Ultrasonic Attenuation in
Liver,” Reflections, June 1981.
- Roseboro, J.A.; Buchanan, P.; Norman, A.; and Stern,
R.: “Effect of Ultrasonic Irradiation on Mammalian
Cells and Chromosomes, in-vitro,” Physics in Medicine
and Biology, v23, no. 2, pp 324-31, March 1978.
- Coover, S.R.; Roseboro, J.A.; and Watson, J.E.: “Electric
Charger for Pocket Ion Chamber Dosimeters,” Health
Physics, v33, no. 5, pp 474-7, November 1977.
- Roseboro, J.A.: “Ultrastructure of Hela Cells
and Thoracic Duct Lymphocytes: Pre and Post –
Ultrasonic Irradiation,” Ultrasound in Medicine,
3B, pp 2063-74, 1977.
- Smokler, M.I.; Anselmo, V.; Frazier, R.; Le Croissette,
D.; and Roseboro, J.A.: “Feasibility Study on
the Design of a Probe for Rectal Cancer Detection,”
JPL Publication (77-Series), May 1977.
- Rollins, E.M.; Saylor, W.L.; and Roseboro, J.A.: “Dosimetry
of Radium-226 Sources with the Fletcher-Suit Gynecological
Applicator,” International Journal of Radiation
Oncology, Biology and Physics, November 1976.
- Roseboro, J.A.; Norman, A.; Machleder, H.J.; Paulus,
H.; and Stern, R.: “The Therapeutic Efficacy of
Ultrasound in Treatment of Autoimmune Disease,”
Ultrasound in Medicine, 2: 487-500, 1976.
- Gopala, Rao U.V.; Rollo, F.D.; and Roseboro, J.A.:
“Tumor Dose-Rate Tables Instead of Central Axis
Depth Dose Data and Tumor-Air-Ratios,” British
Journal of Radiology, 40: 783, 1967.
- Roseboro, J.A.; and Brill, Warren: “Report on
Battelle N.W. Laboratory ---S.W. Radiological Health
Laboratory Alaskan Caribou Muscle Cesium-137 Discrepancies,”
Radiological Health Data, 1965